In Vitro Activities of Antifungal Agents against Clinical Isolates of Dermatophytes from Animals

  • ITOI Sayuri
    Department of Pathobiology, Nihon University School of Veterinary Medicine Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa 252–0880, Japan
  • KANO Rui
    Department of Pathobiology, Nihon University School of Veterinary Medicine Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa 252–0880, Japan
  • HASEGAWA Atsuhiko
    Teikyo University Institute of Medical Mycology Teikyo University Institute of Medical Mycology, 539 Otsuka, Hachioji, Tokyo 192–0395, Japan
  • KAMATA Hiroshi
    Department of Pathobiology, Nihon University School of Veterinary Medicine Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa 252–0880, Japan

書誌事項

タイトル別名
  • <i>In Vitro</i> Activities of Antifungal Agents against Clinical Isolates of Dermatophytes from Animals

この論文をさがす

抄録

Although the susceptibility of dermatophytes to antifungal drugs is well documented in humans, the effectiveness in animals has not been previously investigated. The in vitro susceptibility of 54 clinical isolates from animal dermatophytoses to ketoconazole (KTZ), itaconazole (ITZ) and terbinafine (TFN) was measured using microdilution assay (CLSI M38-A2 test) and by the E-test (KTZ and ITZ). All 3 drugs showed antifungal activity, while KTZ displayed the broadest minimum inhibition concentration (MIC) range (0.125–16 μg/ml) against M. canis and M. gypseum. The MIC of KTZ and ITZ was almost the same for human and animal isolates of T. mentagrophytes and T. rubrum. The MIC of TFN was almost the same for dermatophytes isolated from humans and animals.

収録刊行物

被引用文献 (9)*注記

もっと見る

参考文献 (6)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ