In Vitro Activities of Antifungal Agents against Clinical Isolates of Dermatophytes from Animals
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- ITOI Sayuri
- Department of Pathobiology, Nihon University School of Veterinary Medicine Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa 252–0880, Japan
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- KANO Rui
- Department of Pathobiology, Nihon University School of Veterinary Medicine Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa 252–0880, Japan
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- HASEGAWA Atsuhiko
- Teikyo University Institute of Medical Mycology Teikyo University Institute of Medical Mycology, 539 Otsuka, Hachioji, Tokyo 192–0395, Japan
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- KAMATA Hiroshi
- Department of Pathobiology, Nihon University School of Veterinary Medicine Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa 252–0880, Japan
書誌事項
- タイトル別名
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- <i>In Vitro</i> Activities of Antifungal Agents against Clinical Isolates of Dermatophytes from Animals
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抄録
Although the susceptibility of dermatophytes to antifungal drugs is well documented in humans, the effectiveness in animals has not been previously investigated. The in vitro susceptibility of 54 clinical isolates from animal dermatophytoses to ketoconazole (KTZ), itaconazole (ITZ) and terbinafine (TFN) was measured using microdilution assay (CLSI M38-A2 test) and by the E-test (KTZ and ITZ). All 3 drugs showed antifungal activity, while KTZ displayed the broadest minimum inhibition concentration (MIC) range (0.125–16 μg/ml) against M. canis and M. gypseum. The MIC of KTZ and ITZ was almost the same for human and animal isolates of T. mentagrophytes and T. rubrum. The MIC of TFN was almost the same for dermatophytes isolated from humans and animals.
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 74 (8), 1067-1069, 2012
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681404470784
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- NII論文ID
- 130001879810
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- NII書誌ID
- AA10796138
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- COI
- 1:STN:280:DC%2BC38rhsVSgsg%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 023958273
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- PubMed
- 22467073
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可