Impact of Total Occlusion of an Infarct-Related Artery on Long-Term Mortality in Acute Non-ST-Elevation Myocardial Infarction Patients Who Underwent Early Percutaneous Coronary Intervention
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- Kim Min Chul
- Chonnam National University Hospital
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- Ahn Youngkeun
- Chonnam National University Hospital
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- Rhew Shi Hyun
- Chonnam National University Hospital
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- Jeong Myung Ho
- Chonnam National University Hospital
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- Kim Ju Han
- Chonnam National University Hospital
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- Hong Young Joon
- Chonnam National University Hospital
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- Chae Shung Chull
- Kyungpook National University Hospital
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- Kim Young Jo
- Yeungnam University Hospital
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- Hur Seung Ho
- Keimyung University Hospital
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- Seong In Whan
- Chungnam National University Hospital
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- Chae Jei Keon
- Chonbuk National University Hospital
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抄録
Some patients with non-ST-elevation myocardial infarction (NSTEMI) have a total occlusive infarct-related artery. However, the long-term prognosis of these patients is uncertain, particularly for those who underwent an early invasive strategy. <br>The aim of this study was to determine the clinical impact of total occlusion (TO) of an infarct-related artery (IRA) in these patients. <br>A total of 2,094 patients with NSTEMI who underwent an early invasive strategy with percutaneous coronary intervention (PCI) in the Korea Acute MI Registry (KAMIR) were analyzed (TO group; 665 patients, and non-TO group; 1,429 patients).<br>In-hospital and one-year clinical outcomes were compared between the two groups. The left circumflex (42.9%) and right coronary artery (31.9%) were the major IRA in the TO group, while the left anterior descending artery was more common as an IRA in the non-TO group (44.1%). In-hospital complications including death and cardiogenic shock occurred frequently in the TO group. Also, the rates of one-month and 12-month adverse cardiac outcomes were higher in the TO group. In the Cox-proportional hazard model, TO in IRA predicted 12-month all-cause death. <br>In conclusion, NSTEMI patients with TO in IRA showed worse short- and long-term clinical outcomes compared with those of non-TO patients.
収録刊行物
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- International Heart Journal
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International Heart Journal 53 (3), 160-164, 2012
一般社団法人 インターナショナル・ハート・ジャーナル刊行会