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- Soma Katsura
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Abe Hajime
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Takeda Norihiko
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Shintani Yukako
- Department of Pathology, Faculty of Medicine, The University of Tokyo
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- Takazawa Yutaka
- Department of Pathology, Faculty of Medicine, The University of Tokyo
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- Kojima Toshiya
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Fujiu Katsuhito
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Semba Hiroaki
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Yamashita Hiroshi
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Hirata Yasunobu
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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- Fukayama Masashi
- Department of Pathology, Faculty of Medicine, The University of Tokyo
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- Nagai Ryozo
- Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
この論文をさがす
抄録
Mitral and aortic valve regurgitation is commonly found in osteogenesis imperfecta (OI) patients, however, little is known about the myocardial involvement in this disorder. An 82-year-old man with OI developed heart failure and was admitted to our hospital. Echocardiogram revealed severe mitral regurgitation without left ventricular (LV) dilatation, but with LV wall thickening. Histological analysis exhibited interstitial fibrosis of the myocardium in addition to myxoid changes of the mitral leaflet. These findings suggest that OI patients may develop LV remodeling together with diastolic dysfunction.
収録刊行物
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- International Heart Journal
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International Heart Journal 53 (1), 75-77, 2012
一般社団法人 インターナショナル・ハート・ジャーナル刊行会