Structures of Yadanziosides K, M, N, and O, New Quassinoid Glycosides from <i>Brucea javanica</i> (L.) <scp>Merr</scp>

• Toshiro Sakaki

  Department of Chemistry, Faculty of Science, The University of Tokyo

• Shin Yoshimura

  Department of Chemistry, Faculty of Science, The University of Tokyo

• Takahiko Tsuyuki

  Department of Chemistry, Faculty of Science, The University of Tokyo

• Takeyoshi Takahashi

  Department of Chemistry, Faculty of Science, The University of Tokyo

• Tadashi Honda

  Suntory Institute for Biomedical Research

• Toshihiro Nakanishi

  Suntory Institute for Biomedical Research

抄録

Four new bitter quassinoid glycosides, yadanziosides K, M, N, and O were isolated from Brucea javanica (L.) Merr and their structures were determined by spectral measurement and chemical means. The aglycone of yadanzioside O was found to exhibit a significant antitumor activity against the murine P388 lymphocytic leukemia and this aglycone could be prepared from brusatol.

収録刊行物

• Bulletin of the Chemical Society of Japan

  Bulletin of the Chemical Society of Japan 59 (11), 3541-3546, 1986-11-01

  Oxford University Press (OUP)

キーワード

• General Chemistry

詳細情報

• CRID: 1360565169056073600
• NII論文ID: 130001983305
• DOI: 10.1246/bcsj.59.3541
• ISSN: 13480634
• ISSN: 00092673
• Web Site: https://academic.oup.com/bcsj/article-pdf/59/11/3541/55720475/bcsj.59.3541.pdf
• Web Site: https://search.jamas.or.jp/link/ui/1987113911
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