Lymphocyte-depleted Hodgkin Lymphoma Complicating Hemophagocytic Lymphohistiocytosis as an Initial Manifestation: A Case Report and Review of the Literature
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- Hagihara Masao
- Department of Hematology, Eiju General Hospital, Japan
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- Inoue Morihiro
- Department of Hematology, Eiju General Hospital, Japan
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- Hua Jian
- Department of Hematology, Eiju General Hospital, Japan
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- Iwaki Yasunobu
- Department of Hematology, Eiju General Hospital, Japan
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抄録
Hemophagocytic lymphohistocytosis (HLH) is commonly associated with infectious diseases or T/NK cell-lymphoma; however that with Hodgkin lymphoma (HL) was rarely reported. Herein, we describe a young male diagnosed with lymphocyte-depleted HL (LD-HL) complicated by HLH as an initial manifestation. He was given high-dose steroid therapy plus recombinant thrombomodulin, and subsequent ABVd (doxorubicin, bleomycin, vinblastine, dacarbazine) treatment. In spite of the achievement of a partial remission treated with one cycle of ABVd, he relapsed after 3 cycles. To our knowledge, the present case is very rare, and more intensive treatment might be needed for the long-term control of HLH-complicated HL.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 51 (21), 3067-3072, 2012
一般社団法人 日本内科学会
