Churg-Strauss Syndrome Presenting with Acute Renal Insufficiency Accompanied by Eosinophilic Tubulointerstitial Nephritis
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- Hirohama Daigoro
- Nephrology Center, Toranomon Hospital, Japan
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- Hoshino Junichi
- Nephrology Center, Toranomon Hospital, Japan
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- Sumida Keiichi
- Nephrology Center, Toranomon Hospital, Japan
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- Hasegawa Eiko
- Nephrology Center, Toranomon Hospital, Japan
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- Hiramatsu Rikako
- Nephrology Center, Toranomon Hospital, Japan
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- Yamanouchi Masayuki
- Nephrology Center, Toranomon Hospital, Japan
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- Hayami Noriko
- Nephrology Center, Toranomon Hospital, Japan
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- Suwabe Tatsuya
- Nephrology Center, Toranomon Hospital, Japan
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- Sawa Naoki
- Nephrology Center, Toranomon Hospital, Japan
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- Takemoto Fumi
- Nephrology Center, Toranomon Hospital, Japan
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- Ubara Yoshifumi
- Nephrology Center, Toranomon Hospital, Japan
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- Hara Shigeko
- Health Management Center, Toranomon Hospital, Japan
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- Ohashi Kenichi
- Department of Pathology, Toranomon Hospital, Japan
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- Takaichi Kenmei
- Nephrology Center, Toranomon Hospital, Japan
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抄録
We encountered an unusual and rare case of 59-year-old woman with Churg-Strauss syndrome (CSS) showing myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-related acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis. To date, reports in English of CSS presenting with rapidly progressive/acute renal insufficiency and biopsy-proven renal lesions have been uncommon. Here, we discuss this unusual case and review the previously reported CSS cases. The complication of eosinophilic tubulointerstitial nephritis in CSS cases with acute renal insufficiency might be higher than generally thought. Furthermore, the presence of eosinophilic infiltration and eosinophilic tubulointerstitial nephritis might be associated with the good renal outcome in CSS patients.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 51 (12), 1555-1560, 2012
一般社団法人 日本内科学会