Severe Steroid-resistant Thrombocytopenia Secondary to Cytomegalovirus Infection in an Immunocompetent Adult
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- Sugioka Takashi
- Department of Community Medical Support Institute, Faculty of Medicine, Saga University, Japan
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- Kubota Yasushi
- Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan Department of Transfusion Medicine, Saga University Hospital, Japan
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- Wakayama Kazuo
- Department of Clinical Laboratory Medicine, Saga University Hospital, Japan
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- Kimura Shinya
- Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan
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抄録
Severe thrombocytopenia secondary to cytomegalovirus (CMV) infection is rare in immunocompetent hosts. We describe a case of severe thrombocytopenia secondary to CMV infection in an immunocompetent 30-year-old man who presented with pyrexia and bleeding tendency. A diagnosis of immune thrombocytopenia (ITP) was made following hematological and serological testing, and bone marrow aspiration. Acute CMV infection was confirmed by serological testing, antigenemia, and detection of CMV-DNA. Corticosteroid therapy was ineffective and intravenous immunoglobulin (IVIG) was therefore administered. This resulted in immediate recovery of the platelet count and cessation of nasal bleeding. Early IVIG administration should be considered in steroid-resistant cases.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 51 (13), 1747-1750, 2012
一般社団法人 日本内科学会
