Pulmonary Vein and Superior Vena Cava Isolation for Atrial Fibrillation and Their Long Term Effects on Autonomic Nerve Function

• Iwai Shinsuke

  Saitama Red Cross Hospital, Saitama

• Nitta Junichi

  Saitama Red Cross Hospital, Saitama

• Satou Akira

  Saitama Red Cross Hospital, Saitama

• Inaba Osamu

  Saitama Red Cross Hospital, Saitama

• Yamato Tsunehiro

  Saitama Red Cross Hospital, Saitama

• Asakawa Kihiro

  Saitama Red Cross Hospital, Saitama Department of Cardiovasucular, Tokyo Medical and Dental University

• Hirao Kenzou

  Department of Cardiovasucular, Tokyo Medical and Dental University

• Isobe Mitsuaki

  Department of Cardiovasucular, Tokyo Medical and Dental University

抄録

Background: Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) modifies the autonomic nerve function. The aim of this study is to reveal the time course of heart rate variability (HRV) after pulmonary vein (PV) and superior vena cava (SVC) isolation by long term follow-up. Methods: 84 patients who underwent RFCA of AF were included. PV isolation was performed in 70 patients (PVI-group). The other 14 patients underwent SVC isolation in addition to PVI (SVC-group). HRV was analyzed using 24-hour Holter monitoring performed on average 4 (early-period) and 15 (late-period) months after RFCA. Mean heart rate (MHR), time-domain and frequency-domain were estimated. These parameters were compared with those of 50 normal subjects (Control-group). Results: In early period, both groups had significant increase in MHR and decrease in standard deviation of NN intervals (SDNN) compared with control-group. In addition, SVC-group had even higher MHR (P<0.005) and lower SDNN (P=0.011) than PVI-group. However, MHR returned to the baseline completely in late-period in both groups. SDNN showed significant recovery in late-period, but it was still lower than control-group (P<0.0001). Similarly, some of other parameters in HRV showed incomplete recovery in late-period. Conclusions: Autonomic nerve function of SVC-group was suppressed more than that of PVI-group. HRV in both groups recovered, but not completely to the baseline within 15 months.

収録刊行物

• Journal of Arrhythmia

  Journal of Arrhythmia 27 (Supplement), OP10_3-, 2011

  日本不整脈学会

キーワード

• atrial fibrillation
• heart rate variability

詳細情報

• CRID: 1390282680222532608
• NII論文ID: 130002130470
• DOI: 10.4020/jhrs.27.op10_3
• ISSN: 18832148
• ISSN: 18804276
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可