Examining Validity of Diagnostic Criteria for Metabolic Syndrome through Comparison with Visceral Fat Area in Japanese Men

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  • 日本人男性における内臓脂肪面積からみるメタボリックシンドローム診断基準の有用性の検討
  • ニホンジン ダンセイ ニ オケル ナイゾウ シボウ メンセキ カラ ミル メタボリックシンドローム シンダン キジュン ノ ユウヨウセイ ノ ケントウ

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Abstract

Objective: We examined the validity of waist circumference measurement and subsequent diagnostic criteria for metabolic syndrome (MS) by comparing them with the visceral fat area measured by an abdominal CT scan.<br>Subjects and Methods: Our subjects were 194 males. We recorded their age, height (cm), weight (kg), body mass index, waist circumference (cm), maximum blood pressure (mmHg), minimum blood pressure (mmHg), HDL cholesterol (mg/dl), triglycerides (mg/dl), fasting glucose (mg/dl), visceral fat area (cm2), and subcutaneous fat area (cm2). Through comparison with the visceral fat area, referred to as the optimal criterion, we examined the validity of waist circumference measurement by calculating its sensitivity, specificity, and positive likelihood ratio. We selected subjects with an abnormal waist circumference and 2 or more abnormal values from among diagnostic criteria for MS, and examined the validity of their waist circumference measurement by calculating the sensitivity, specificity, and positive likelihood ratio, using the visceral fat area as the optimal criterion. <br>Results: The miss rate for waist circumference measurement was low and its sensitivity high. We did not observe any relationships between the subsequent diagnostic criteria for MS and visceral fat area.<br>Conclusion: We believe that there is valid relationship between visceral fat area and waist circumference measurement, in view of the low miss rate and high sensitivity observed for this diagnostic criterion for MS. Our results suggested that the validity of subsequent diagnostic criteria referred to after waist circumference measurement requires further examination.

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