Pregnancy-Related Acute Myocardial Infarction in Japan

DOI Web Site PubMed 被引用文献6件 参考文献28件
  • Satoh Hiroshi
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine
  • Sano Makoto
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine
  • Suwa Kenichiro
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine
  • Saotome Masao
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine
  • Urushida Tsuyoshi
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine
  • Katoh Hideki
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine
  • Hayashi Hideharu
    Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine

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タイトル別名
  • – A Review of Epidemiology, Etiology and Treatment From Case Reports –

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Background: Pregnancy-related acute myocardial infarction (AMI) is uncommon, but can result in maternal and/or fetal death. This study retrospectively reviews pregnancy-related AMI reported from medical institutions in Japan. Methods and Results: We electronically or manually searched the literature for reports of pregnancy-related AMI between 1981 and 2011. In total, 62 patients were described and the numbers increased in accordance with the rising average age of the mothers. AMI occurred frequently in women aged 30–34 years (mean age, 33), in the third trimester and postpartum (n=11 and n=28, respectively). The prevalence of conventional risk factors was relatively low (n=21). On the other hand, 29 patients had obstetric and/or non-obstetric complications, and 24 received medication. Only 8 AMI were caused by atherosclerosis, while coronary dissection, thrombus and spasm were the cause in 14, 9 and 12 cases, respectively. All patients with atherosclerosis had conventional risk factors, and some patients with spasm had a history of smoking. Medication with ergot derivatives was associated mostly with spasm, whereas ritodrine was potentially related to dissection. Conclusions: The prevalence of pregnancy-related AMI in Japan seems lower than in Western countries, and the etiology differs considerably. However, as the trend of later childbearing continues, more pregnant women have more risk factors, complications, and require medication. Cardiologists and obstetricians must consider the increased risk of AMI.  (Circ J 2013; 77: 725–733)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 77 (3), 725-733, 2013

    一般社団法人 日本循環器学会

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