<b>小児の急性気管支炎におけるベータ2刺激薬の処方実態</b>

• 神垣 有美

  国立精神・神経医療研究センター精神保健研究所精神薬理研究部

• 大森 崇

  同志社大学文化情報学部文化情報学科

• 小田嶋 博

  独立行政法人国立病院機構福岡病院

• 佐藤 俊哉

  京都大学大学院医学研究科社会健康学系専攻医療統計学分野

書誌事項

タイトル別名

• <b>On Prescription of Beta 2 Agonists for Pediatric Patients </b><b>with Acute Bronchitis in Japan </b>

抄録

Objective: In Japan, beta 2 agonist (BA) has an indication for acute bronchitis with airway obstruction. To investigate BA prescribing practices for children whose diagnosis were acute bronchitis without asthma in Japan, a database study and interviews with pediatricians were conducted.<br>Design: Database study<br>Methods: We conducted a database study. Using the Japan Medical Data Center database, medical receipts of about 100,000 children younger than 18 years old were obtained between 2005 and 2008. First we identified all the new incidences (362,287 cases) of upper respiratory tract infection, influenza, or acute bronchitis. Outcome measure was prescription of BA within 21 days of the incidence. We calculated the prescription proportions of BA for the asthma group (41,064 cases) and the non-asthma group (321,223 cases). We then interviewed 10 pediatricians to elucidate the reason why they prescribe BA for patients.<br>Results: The proportion of children prescribed BA at least once a year in 3-5 years old was 49.9 %. Among 3-5 year olds with acute bronchitis, the BA prescription proportions in the asthma group (58.6%) was nearly as high as that in the non-asthma group (56.6%). Although BA prescription proportions in the asthma group decreased annually with the exception of 0-2 years old, those in the non-asthma group remain unchanged. Based on the interview study, we found interpretations of airway obstruction for acute bronchitis without asthma were broadly-divided into 2 types: the effect of inducing bronchospasm and the effect of producing large amounts of secretions in the airways.<br>Conclusion: In this study, it was revealed that pediatric patients with acute bronchitis were commonly prescribed BA in Japan. To promote an appropriate use of BA, prescriptions of BA to non-asthma pediatric patients should be carefully watched. (Jpn J Pharmacoepidemiol 2012; 17(1): 1-12)

収録刊行物

• 薬剤疫学

  薬剤疫学 17 (1), 1-12, 2012

  一般社団法人 日本薬剤疫学会

キーワード

• ベータ2刺激薬
• 急性気管支炎
• 処方実態調査
• 小児

詳細情報

• CRID: 1390282679460806912
• NII論文ID: 130003297452
• DOI: 10.3820/jjpe.17.1
• ISSN: 1882790X
• ISSN: 13420445
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可