Osteomalacia and Insufficiency Fracture in a Hemodialysis Patient with Autosomal Dominant Polycystic Kidney Disease

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A 61-year-old Japanese woman on hemodialysis with autosomal dominant polycystic kidney disease (ADPKD) was admitted to the hospital with gluteal pain. Radiographs demonstrated a fracture of the left pubis. The serum 1,25(OH)2-vitamin D and 25(OH)-vitamin D levels were low. A biopsy of the right iliac crest disclosed osteomalacia. Active vitamin D sterol was administered in conjunction with dietary modification. Her gluteal pain was resolved three years later, and healing of the fracture was confirmed by radiology. This case emphasizes that vitamin D deficiency and malnutrition can cause osteomalacia in dialysis patients, even if calcium (Ca) and phosphate (P) levels are controlled by calcium carbonate.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 51 (23), 3277-3280, 2012

    一般社団法人 日本内科学会

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