CD5-Positive Diffuse Large B Cell Lymphoma Infiltrating the Central Nervous System Presenting Guillain-Barr^|^eacute;-Like Syndrome after Chemotherapy
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- Machida Hisanori
- Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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- Shinohara Tsutomu
- Department of Clinical Investigation National Hospital Organization National Kochi Hospital
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- Hatakeyama Nobuo
- Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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- Okano Yoshio
- Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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- Nakano Mayuri
- Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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- Tobiume Makoto
- Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
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- Naruse Keishi
- Division of Pathology National Hospital Organization National Kochi Hospital
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- Iwahara Yoshihito
- Division of Internal Medicine National Hospital Organization National Kochi Hospital
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- Ogushi Fumitaka
- Division of Pulmonary Medicine National Hospital Organization National Kochi Hospital
書誌事項
- タイトル別名
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- CD5-Positive Diffuse Large B Cell Lymphoma Infiltrating the Central Nervous System Presenting Guillain-Barré-Like Syndrome after Chemotherapy
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抄録
An 83-year-old woman was admitted to our hospital with abdominal pain. Examination revealed mediastinal lymphoadenopathy, hepatosplenomegaly, and infiltration of abnormal cells into the bone marrow with hemophagocytosis, and CD5-positive diffuse large B cell lymphoma was diagnosed. Chemotherapy was administered and progressive weakness of the limbs, resembling a Guillain-Barré-like syndrome, subsequently appeared. Cerebrospinal fluid examination indicated lymphoma cell infiltration. Although immune globulin and steroid therapies were not effective, intrathecal injection of methotrexate, predonisolone, and cytarabine improved these symptoms. Subsequent to chemotherapy, cell surface antigen changes were observed in the cerebrospinal fluid relative to those in bone marrow. [J Clin Exp Hematopathol 52(3) : 199-204, 2012]
収録刊行物
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- Journal of Clinical and Experimental Hematopathology
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Journal of Clinical and Experimental Hematopathology 52 (3), 199-204, 2012
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詳細情報 詳細情報について
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- CRID
- 1390282679682561408
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- NII論文ID
- 10031143564
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- NII書誌ID
- AA11556796
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- COI
- 1:STN:280:DC%2BC3s3ksl2lsg%3D%3D
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- ISSN
- 18809952
- 13464280
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- PubMed
- 23269080
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可