書誌事項
- タイトル別名
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- A case of Wilson disease treated as schizophrenia for 20 years
- ショウレイ ホウコク チョウキ ニ ワタリ トウゴウ シッチョウショウ ト シテ カリョウ サレタ ウイルソンビョウ ノ 1レイ
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A 42-year-old man, who had been diagnosed as schizophrenia due to memory disturbance, mental disorder and delusion of persecution at age of 20, was referred to our hospital due to progressive neurological symptoms and unknown liver dysfunction. He had previously been diagnosed as nonalcoholic steatohepatitis or drug-induced liver injury in some other hospitals. Later, he presented with difficulty in walking and akinesia like drug-induced parkinsonism.<br> On admission, his laboratory findings showed low levels of serum ceruloplasmin and the increase of 24-h urinary copper excretion. Kayser-Fleischer rings were demonstrated. Histological examination of the liver revealed cirrhosis and the hepatic copper concentration was elevated. MRI of the brain showed high-intensity signal area at the basal ganglia. We diagnosed him as Wilson disease and started treatment with trientine and zinc acetate, and also started rehabilitation. His mental disorder, parkinsonism and biochemical data have apparently improved after the initiation of the treatment.<br>
収録刊行物
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- 肝臓
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肝臓 53 (12), 814-820, 2012
一般社団法人 日本肝臓学会
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詳細情報 詳細情報について
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- CRID
- 1390001204793480576
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- NII論文ID
- 10031144305
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- NII書誌ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL書誌ID
- 024164515
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
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- 使用不可