高脂血症における血清アポリポ蛋白濃度とLDLサブクラスの分布

• 宍野 宏治

  愛媛大学医学部附属病院検査部

• 佐伯 修一

  愛媛大学保健管理センター

• 武内 望

  松山記念病院

書誌事項

タイトル別名

• Distribution of the LDL Subclasses and Apolipoprotein Levels in Hyperlipidemias

抄録

LDL subclasses were determined by nondenaturing polyacrylamide slab gel electrophoresis in sera from normal and hyperlipidemic subjects (IIa, IIb and IV) and their size distributions were examined with reference to the levels of apolipoproteins. Apolipoproteins B, C-II, C-III and E were significantly high in sera from hyperlipidemic patients, while there was no significant difference in the level of apolipoprotein A-I. The smaller LDL subclasses (Rf = 0.80, 0.84, 0.92) appeared in hyperlipidemic patients but not in normal subjects. Smaller LDL subclasses showed increased prevalence among patients with hyperapolipoproteinemia and tended to be increased among patients with vascular complications; cerebral infarction, myocardial infarction, hypertension and diabetes mellitus with complications.

収録刊行物

• Japanese Journal of Clinical Chemistry

  Japanese Journal of Clinical Chemistry 26 (3), 134-142, 1997

  一般社団法人 日本臨床化学会

キーワード

• 低比重リボ蛋白 (LDL)
• アポ蛋白
• 高トリグリセライド血症

詳細情報

• CRID: 1390001204912288512
• NII論文ID: 130003357830
• NII論文ID: 10011508867
• NII書誌ID: AN00252758
• DOI: 10.14921/jscc1971b.26.3_134
• COI: 1:CAS:528:DyaK2sXmslantrc%3D
• ISSN: 21874077
• ISSN: 03705633
• Web Site: https://search.jamas.or.jp/link/ui/1998050777
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可