Human Genomics in Cardiovascular Medicine

• Morita Hiroyuki

  Department of Translational Research for Healthcare and Clinical Science, Graduate School of Medicine, The University of Tokyo

書誌事項

タイトル別名

• – Implications and Perspectives –

抄録

For the past 10 years in the post-genomic era, emerging technologies in human genomic research have provided us with a plethora of genetic variations implicated in the pathogenesis of cardiovascular diseases. Discovering the key target genes in genomic research has contributed to biomedical research on the mechanical pathways of the diseases. In an era with dramatic development of brand new strategies, the conventional evaluation of family aggregation, environmental exposure and clinical phenotype remains of great importance to promote genomic research. Notwithstanding the promising progress in genomic research, we still have an enormous number of issues to overcome before approaching the ultimate goal of human genomics: the successful application of genomic data to personalized medicine.  (Circ J 2013; 77: 876–885)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 77 (4), 876-885, 2013

  一般社団法人 日本循環器学会

キーワード

• Clinical application
• Genetic variant
• Genome-wide association study (GWAS)
• Human genomics

詳細情報

• CRID: 1390282680080117248
• NII論文ID: 10031138983
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-13-0126
• COI: 1:STN:280:DC%2BC3svkt1Cqug%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• PubMed: 23470884
• Web Site: https://www.jstage.jst.go.jp/article/circj/77/4/77_CJ-13-0126/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2014027893
• 本文言語コード: en
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