Multilocus Sequence Typing and DNA Similarity Analysis Implicates that a Borrelia valaisiana-related sp. Isolated in Japan is Distinguishable from European B. valaisiana

• KAWABATA Hiroki

  Department of Bacteriology-I, National Institute of Infectious Diseases, Tokyo 162–8640, Japan

• TAKANO Ai

  Department of Bacteriology-I, National Institute of Infectious Diseases, Tokyo 162–8640, Japan Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677–1 Yoshida, Yamaguchi 753–8515, Japan

• KADOSAKA Teruki

  Department of Infection and Immunity, Aichi Medical University, Aichi 480–1195, Japan

• FUJITA Hiromi

  Mahara Institute of Medical Acarology, Tokushima 779–1510, Japan

• NITTA Yoshiki

  Okinawa Prefectural Institute of Animal Health, Okinawa 900–0024, Japan

• GOKUDEN Mutsuyo

  Kagoshima Prefectural Institute of Environmental Research and Public Health, Kagoshima 892–0853, Japan

• HONDA Toshiro

  Kagoshima Prefectural Institute of Environmental Research and Public Health, Kagoshima 892–0853, Japan Kaseda Public Health Center, Kagoshima 897–0001, Japan

• TOMIDA Junko

  School of Pharmacy, Aichi Gakuen University, Aichi 464–8650, Japan

• KAWAMURA Yoshiaki

  School of Pharmacy, Aichi Gakuen University, Aichi 464–8650, Japan

• MASUZAWA Toshiyuki

  Faculty of Pharmaceutical Sciences, Chiba Institute of Science, Chiba 288–0025, Japan

• ISHIGURO Fubito

  Fukui Prefectural Institute of Health and Environmental Science, Fukui 910–8551, Japan

• TAKADA Nobuhiro

  Department of Pathological Sciences, Faculty of Medical Sciences, University of Fukui, Fukui 910–1193, Japan

• YANO Yasuhiro

  Department of Pathological Sciences, Faculty of Medical Sciences, University of Fukui, Fukui 910–1193, Japan

• ANDOH Masako

  Department of Virology I, National Institute of Infectious Diseases, Tokyo 162–8640, Japan

• ANDO Shuji

  Department of Virology I, National Institute of Infectious Diseases, Tokyo 162–8640, Japan

• SATO Kozue

  Department of Bacteriology-I, National Institute of Infectious Diseases, Tokyo 162–8640, Japan

• TAKAHASHI Hideyuki

  Department of Bacteriology-I, National Institute of Infectious Diseases, Tokyo 162–8640, Japan

• OHNISHI Makoto

  Department of Bacteriology-I, National Institute of Infectious Diseases, Tokyo 162–8640, Japan

書誌事項

タイトル別名

• Multilocus Sequence Typing and DNA Similarity Analysis Implicates that a <i>Borrelia valaisiana</i>–related sp. Isolated in Japan is Distinguishable from European <i>B. valaisiana</i>

抄録

Lyme disease Borrelia spp. are transmitted by Ixodes ticks, and more than 10 species of borreliae have been identified around the world. Recently, another Borrelia sp. has been reported in Asia (Japan, Korea, China, Taiwan and Thailand) as Borrelia valaisiana-related sp. In the present study, we obtained and genetically characterized 19 B. valaisiana-related sp. strains from mammals and ticks. Genetic analyses showed that the Borrelia strains were distinct from B. valaisiana found in Europe. Multilocus sequence typing revealed that these Borrelia isolates formed a monophyletic group with B. yangtze strains in China. Some of the strains were isolated from the bladders of small mammals, and also two strains were experimentally confirmed to be infectious in C3H/HeN mice. We observed that the Borrelia sp. was maintained in the Ixodes granulatus tick after molting. These results suggested that small mammals and I. granulatus were possible reservoir hosts and the vector tick for the Borrelia sp., respectively. B. valaisiana, originally found in Europe, was transmitted mainly by I. ricinus, and birds were mainly thought to be reservoir hosts. Our results suggested that Japanese isolates of B. yangtze (formerly B. valaisiana-related sp.) were distinguishable from B. valaisiana according to the reservoir host and its vector tick. In this study, we also deposited borrelia strain Okinawa-CW62 into bioresource centers as a reference strain of B. yangtze(=DSM 24625, JCM 17189).

収録刊行物

• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ

  Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 75 (9), 1201-1207, 2013

  公益社団法人 日本獣医学会

キーワード

• <i>Borrelia valaisiana</i>-related sp.
• <i>Borrelia yangtze</i>
• <i>Ixodes granulatus</i>
• MLST
• tick-borne zoonotic diseases

詳細情報

• CRID: 1390001206428772352
• NII論文ID: 130003362209
• NII書誌ID: AA10796138
• DOI: 10.1292/jvms.13-0162
• COI: 1:STN:280:DC%2BC3snjtVKntA%3D%3D
• ISSN: 13477439
• ISSN: 09167250
• NDL書誌ID: 024906864
• PubMed: 23665530
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I024906864
• Web Site: https://www.jstage.jst.go.jp/article/jvms/75/9/75_13-0162/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2014115993
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可