Spontaneous Rhabdomyosarcoma in a Common Marmoset (Callithrix jacchus)
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- TOCHITANI Tomoaki
- Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
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- MATSUMOTO Izumi
- Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
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- HOSHINO Kohei
- Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
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- TOYOSAWA Kaoru
- Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
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- KOUCHI Mami
- Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
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- KOUJITANI Takatoshi
- Genomic Science Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
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- KIMURA Juki
- Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
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- FUNABASHI Hitoshi
- Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasugade-naka, Konohana-ku, Osaka 554-0022, Japan
書誌事項
- タイトル別名
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- Spontaneous Rhabdomyosarcoma in a Common Marmoset (<i>Callithrix jacchus</i>)
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抄録
The common marmoset (Callithrix jacchus) is now widely used in various research fields, including toxicology. However, information about the background pathology of this species is scarce. Here, we report a case of rhabdomyosarcoma that spontaneously occurred in a common marmoset. A 44-month-old male common marmoset was euthanized due to bilateral hind limb paralysis. At necropsy, a 2×2×5-cm intramuscular mass was observed in the lower right back. Histologically, the mass was mainly composed of interlacing bundles of spindle-shaped tumor cells. Immunohistochemically, the tumor cells were positive for myogenin, desmin, vimentin and alpha-smooth muscle actin. Ultrastructurally, the tumor cells contained bundles of myofilaments with Z-band-like structures. Thus, the tumor was diagnosed as a rhabdomyosarcoma. To our knowledge, this is the first report of spontaneous rhabdomyosarcoma that was definitely diagnosed in the common marmoset.
収録刊行物
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- Journal of Toxicologic Pathology
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Journal of Toxicologic Pathology 26 (2), 187-191, 2013
日本毒性病理学会
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詳細情報 詳細情報について
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- CRID
- 1390001204414139904
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- NII論文ID
- 130003362365
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- NII書誌ID
- AN10232280
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- COI
- 1:STN:280:DC%2BC3sfmslWiug%3D%3D
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- ISSN
- 1881915X
- 09149198
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- NDL書誌ID
- 024792418
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- PubMed
- 23914060
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可