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- GANAU Mario
- Chair of Neurosurgery, University of Cagliari
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- ENNAS Franco
- Chair of Neurosurgery, University of Cagliari
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- BELLISANO Giulia
- Institute of Anatomic Pathology, University of Cagliari
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- GANAU Laura
- Chair of Neurosurgery, University of Cagliari
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- AMBU Rossano
- Institute of Anatomic Pathology, University of Cagliari
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- FAA Gavino
- Institute of Anatomic Pathology, University of Cagliari
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- MALECI Alberto
- Chair of Neurosurgery, University of Cagliari
書誌事項
- タイトル別名
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- —Pathological Considerations and Surgical Strategy—
この論文をさがす
抄録
Symptomatic lumbar synovial cysts (LSCs) are a rare cause of degenerative narrowing of the spinal canal, with thecal sac or nerve root compression. True synovial cysts have a thick wall lined by synovial cells, containing granulation tissue, numerous histiocytes, and giant cells. In contrast, pseudo-cysts lack specialized epithelium, have a collagenous capsule filled with myxoid material, and may be classified into ganglion cysts, originating from periarticular fibrous tissues, and ligamentous cysts, arising from the ligamentum flavum or even from the posterior longitudinal ligament. Here we present the surgical series of the Chair of Neurosurgery at the University of Cagliari (Italy) including a total of 17 LSCs. Surgical technique consisted of facet sparing excision of LSC, achieved by simple hemilaminectomy/laminectomy, and diagnosis was always confirmed by histological specimen examination, which detected the typical synovial epithelium, the intracystic presence of hemosiderin, histiocytes, and calcifications. Further immunohistochemical investigation revealed positive staining for cytokeratin: CK5, CK6, and AE1/AE3. Clinically, our cohort experienced rapid and complete resolution of symptoms, without perioperative complications, or recurrence of cysts or vertebral instability at a median follow up of 28 months, when the MacNab score was generally excellent. A review of the literature, retrieving articles published from 1973, collected a total of 101 articles concerning all the cases of LSC scientifically described to date. Both clinical and histological findings described in our study support the theory of degenerative microtraumatic pathogenesis of synovial cysts.<br>
収録刊行物
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- Neurologia medico-chirurgica
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Neurologia medico-chirurgica 53 (2), 95-102, 2013
一般社団法人 日本脳神経外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001205058754560
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- NII論文ID
- 10031138782
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- NII書誌ID
- AN00358613
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- COI
- 1:STN:280:DC%2BC3svhtlajsA%3D%3D
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- ISSN
- 13498029
- 04708105
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- PubMed
- 23438660
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可