Anti-Aquaporin-4 Antibody-Seronegative NMO Spectrum Disorder with Baló's Concentric Lesions
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- Masuda Hiroki
- Department of Neurology, Narita Red Cross Hospital, Japan
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- Mori Masahiro
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
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- Katayama Kaoru
- Department of Neurology, Narita Red Cross Hospital, Japan
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- Kikkawa Yuriko
- Department of Neurology, Narita Red Cross Hospital, Japan
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- Kuwabara Satoshi
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
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抄録
A 34-year-old woman developed simultaneous bilateral severe optic neuritis and subsequent myelitis. Two months after the first attack, she developed a headache and dysesthesia in the left arm. Brain magnetic resonance imaging revealed multiple hyperintense lesions in the white matter of the right hemisphere, some of which were Baló-like concentric lesions. Our diagnosis was neuromyelitis optica spectrum disorder with Baló's concentric sclerosis (BCS), although the patient was negative for anti-aquaporin-4 (anti-APQ4) antibodies. Our case suggests that Baló's concentric sclerosis overlaps with neuromyelitis optica spectrum disorder and that this overlapping is caused by a mechanism that does not involve anti-AQP4 antibodies.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 52 (13), 1517-1521, 2013
一般社団法人 日本内科学会