Glucocorticoid-induced Normotensive Scleroderma Renal Crisis: A Report on Two Cases and a Review of the Literature in Japan
-
- Maruyama Akihito
- Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan
-
- Nagashima Takao
- Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan
-
- Ikenoya Kohei
- Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan
-
- Aoki Yoko
- Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan
-
- Matsuyama Yasushi
- Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan
-
- Iwamoto Masahiro
- Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan
-
- Minota Seiji
- Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan
この論文をさがす
抄録
We herein report the findings of 2 cases of normotensive scleroderma renal crisis (SRC) that developed soon after the commencement of a glucocorticoid therapy. We also review 8 cases of normotensive SRC reported in Japan, including our cases. The common characteristics of these 8 cases are as follows: the recent onset of systemic sclerosis, the presence of diffuse skin sclerosis, the presence of myositis and/or serositis, a high titer of antinuclear antibody and positivity for anti-Scl-70 antibody. In 7 of the 8 patients, thrombotic microangiopathy developed within one month of starting the glucocorticoid treatment. We should be careful with the use of glucocorticoids in systemic sclerosis patients exhibiting these features in order to avoid cases of normotensive SRC.<br>
収録刊行物
-
- Internal Medicine
-
Internal Medicine 52 (16), 1833-1837, 2013
一般社団法人 日本内科学会