An Autopsy Case of the Marburg Variant of Multiple Sclerosis (Acute Multiple Sclerosis)
-
- Suzuki Makiko
- The First Department of Medicine, Department of Neurology, Hamamatsu University School of Medicine, Japan
-
- Kawasaki Hideya
- Regenerative & Infectious Pathology, Hamamatsu University School of Medicine, Japan
-
- Masaki Katsuhisa
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan
-
- Suzuki Satoshi O.
- Department of Neuropathology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan
-
- Terada Tatsuhiro
- The First Department of Medicine, Department of Neurology, Hamamatsu University School of Medicine, Japan
-
- Tsuchida Takashi
- Department of Pathology, Hamamatsu University School of Medicine, Japan
-
- Tokuyama Tsutomu
- Department of Neurosurgery, Hamamatsu University School of Medicine, Japan
-
- Kono Satoshi
- The First Department of Medicine, Department of Neurology, Hamamatsu University School of Medicine, Japan
-
- Komori Takashi
- Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Japan
-
- Baba Satoshi
- Department of Pathology, Hamamatsu University School of Medicine, Japan
-
- Kira Jun-ichi
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan
-
- Miyajima Hiroaki
- The First Department of Medicine, Department of Neurology, Hamamatsu University School of Medicine, Japan
この論文をさがす
抄録
We herein report an autopsy case of the Marburg variant of multiple sclerosis (MS). A 29-year-old woman developed acute and progressive neurological symptoms. A diagnosis of MS was suspected based on the patient's clinical background and brain MRI findings and the lack of evidence of malignancy on a brain biopsy. Despite the administration of typical treatment for MS, a fatal outcome occurred three months after disease onset. The autopsy revealed multiple inflammatory demyelinating lesions in the central nervous system. In addition, two noteworthy histopathological features were observed compared with prototypical MS. We evaluate the pathogenic differences between the Marburg type and prototypical MS by discussing the neuropathology and cerebrospinal fluid (CSF) findings of our case.<br>
収録刊行物
-
- Internal Medicine
-
Internal Medicine 52 (16), 1825-1832, 2013
一般社団法人 日本内科学会