Sweet's Syndrome Complicated by Kikuchi's Disease and Hemophagocytic Syndrome which Presented with Retinoic Acid-inducible Gene-I in both the Skin Epidermal Basal Layer and the Cervical Lymph Nodes

DOI 機関リポジトリ HANDLE Web Site PubMed 参考文献8件
  • Koga Tomohiro
    Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Japan
  • Takano Kanako
    Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Japan
  • Horai Yoshiro
    Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Japan
  • Yamasaki Satoshi
    Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Japan
  • Nakamura Hideki
    Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Japan
  • Mizokami Akinari
    Department of Rheumatology, Nagasaki Municipal Hospital, Japan
  • Ohshima Koichi
    Department of Pathology, Kurume University School of Medicine, Japan
  • Kawakami Atsushi
    Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Japan

この論文をさがす

抄録

A 21-year-old man was admitted to our hospital with a fever, erythema, cervical lymphadenopathy and pancytopenia. A diagnosis of Sweet's syndrome (SS) with Kikuchi's disease (KD) and hemophagocytic syndrome (HPS) was made based on the results of a bone marrow aspiration along with the results from biopsy specimens of the brachial skin and a cervical lymph node. The expression of retinoic acid-inducible gene-I (RIG-I) in the skin epidermal basal layer as well as in a cervical lymph node was revealed through immunohistochemistry. He successfully entered remission through treatment with prednisolone. This findings of this case indicate that when SS with KD presents as HPS, it may suggest an association with an RIG-I-related innate immunity.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 52 (16), 1839-1843, 2013

    一般社団法人 日本内科学会

参考文献 (8)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ