書誌事項
- タイトル別名
-
- Modified TPF Chemotherapy for Pulmonary Metastases from Squamous Cell Carcinoma of the Head and Neck
- リンショウ アタマ ケイブ ヘンペイ ジョウヒガン ハイ テンイレイ ニ タイスル TPF リョウホウ ヘンポウ ノ ケントウ(ダイ2ホウ)
この論文をさがす
抄録
We report herein on 15 cases of pulmonary metastases from squamous cell carcinoma of the head and neck (SCCHN) treated with modified TPF chemotherapy (docetaxel combined with nedaplatin and 5-FU). TPF chemotherapy is known as a neoajuvant chemotherapy regimen. We modified the TPF chemotherapy using nedaplatin as a substitute for cisplatin. We tried 4 courses of modified TPF chemotherapy every 3 weeks, docetaxel 60 mg/m2 on day 1; nedaplatin 75 mg/m2 on day 1 and 5-FU 1000 mg/body by continuous infusion on days 1 to 4. 11 patients received 4 courses, and the remaining of 4 patients recieved 1-3 courses because of their poor general condition. Of the 15 patients, 13 were males and 2 were females with ages ranging from 43 to 73 years (mean, 59.1 yr). Two of the primary sites were in the nasopharynx, 2 in orophanrynx, 4 in the hypopharynx, 2 in the larynx and 4 in the oral cavity. Clinically there were 7 complete responders, 4 partial responders, 2 with no change, and 2 with progressive disease. The mean overall survival was 46.5 months. TPF chemotherapy may improve the overall survival.<br>
収録刊行物
-
- 耳鼻咽喉科臨床
-
耳鼻咽喉科臨床 106 (1), 61-65, 2013
耳鼻咽喉科臨床学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679247256064
-
- NII論文ID
- 10031141239
-
- NII書誌ID
- AN00107089
-
- ISSN
- 18844545
- 00326313
-
- NDL書誌ID
- 024209974
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可