Antibacterial Activity of Pd(II) Complexes with Salicylaldehyde-Amino Acids Schiff Bases Ligands

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  • Rîmbu Cristina
    Faculty of Veterinary Medicine, Microbiology-Immunology Department Iaşi, University of Agricultural Sciences and Veterinary Medicine Iaşi
  • Danac Ramona
    Faculty of Chemistry, Alexandru Ioan Cuza from Iaşi University
  • Pui Aurel
    Faculty of Chemistry, Alexandru Ioan Cuza from Iaşi University

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Palladium(II) complexes with Schiff bases ligands derived from salicylaldehyde and amino acids (Ala, Gly, Met, Ser, Val) have been synthesized and characterized by Fourier transform (FT)-IR, UV-Vis and 1H-NMR spectroscopy. The electrospray mass spectrometry (ES-MS) spectrometry confirms the formation of palladium(II) complexes in 1/2 (M/L) molar ratio. All the Pd(II) complexes 1, [Pd(SalAla)2]Cl2; 2, [Pd(SalGly)2]Cl2; 3, [Pd(SalMet)2]Cl2; 4, [Pd(SalSer)2]Cl2; 5, [Pd(SalVal)2]Cl2; have shown antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli.

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