Successful Treatment of Histiocytic Sarcoma and Concurrent HIV Infection Using a Combination of CHOP and Antiretroviral Therapy
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- Narita Kosuke
- Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
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- Noro Rintaro
- Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
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- Seike Masahiro
- Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
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- Matsumoto Masaru
- Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
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- Fujita Kazue
- Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
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- Matsumura Jiro
- Department of Microbiology and Immunology, Nippon Medical School, Japan
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- Takahashi Mikiko
- Department of Analytic Human Pathology, Nippon Medical School, Japan
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- Kawamoto Masashi
- Department of Clinical Pathology, University Hospital, Mizonokuchi, Teikyo University School of Medicine, Japan
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- Gemma Akihiko
- Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
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抄録
Histiocytic sarcoma (HS) is a rare malignancy of soft tissues with an unknown etiology. The CHOP (cyclophosphamide, vincristine sulfate, doxorubicin hydrochloride and prednisolone) regimen is often adopted as first-line chemotherapy; however, its therapeutic efficacy against HS is usually low. We herein first present the case of a patient with HS who was infected with human immunodeficiency virus-1 (HIV) in whom treatment with a combination of CHOP and antiretroviral therapy (ART) was successful. The patient has been in complete remission for 12 months following the discontinuation of chemotherapy under continuous ART. This case report may help to promote further investigation of both HS and HIV-related malignancy. <br>
収録刊行物
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- Internal Medicine
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Internal Medicine 52 (24), 2805-2809, 2013
一般社団法人 日本内科学会