Acute Kidney Injury in a Patient with Polyarteritis Nodosa and Multiple Myeloma

  • Yokota Kazuhiro
    Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan
  • Inoue Tsutomu
    Department of Nephrology, Saitama Medical University, Japan
  • Akiyama Yuji
    Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan
  • Kajiyama Hiroshi
    Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan
  • Funakubo Asanuma Yu
    Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan
  • Arai Eiichi
    Department of Pathology, Saitama Medical University, Japan
  • Suzuki Hiromichi
    Department of Nephrology, Saitama Medical University, Japan
  • Mimura Toshihide
    Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan

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抄録

We herein report the case of a Japanese man with polyarteritis nodosa (PAN) accompanied by multiple myeloma (MM). The patient was diagnosed with PAN. Concurrently, IgG kappa paraprotein was detected, and bone marrow changes indicative of MM were observed. Prednisolone (PSL) administered at a dose of 30 mg/day was initiated; however, the serum creatinine level increased. In spite of increasing the dose of PSL to 45 mg/day and initiating treatment with double filtration plasmapheresis, the patient's renal dysfunction continued to progress and haemodialysis was introduced. He died from pneumonia 12 months after admission. We conclude that renal failure is an important risk factor in the prognosis of PAN accompanied by MM.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 53 (3), 263-267, 2014

    一般社団法人 日本内科学会

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