Eradication of H. pylori infection in patients allergic to penicillin using triple therapy with a PPI, metronidazole and sitafloxacin.

• Furuta Takahisa

  Center for Clinical Research, Hamamatsu University School of Medicine, Japan

• Sugimoto Mitsushige

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Yamade Mihoko

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Uotani Takahiro

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Sahara Shu

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Ichikawa Hitomi

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Kagami Takuma

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Yamada Takanori

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Osawa Satoshi

  Department of Endoscopic and Photodynamic Medicine, Hamamatsu University School of Medicine, Japan

• Sugimoto Ken

  First Department of Medicine, Hamamatsu University School of Medicine, Japan

• Watanabe Hiroshi

  Department of Clinical Pharmacology & Therapeutics, Hamamatsu University School of Medicine, Japan

• Umemura Kazuo

  Department of Pharmacology, Hamamatsu University School of Medicine, Japan

書誌事項

タイトル別名

• Eradication of <i>H. pylori</i> Infection in Patients Allergic to Penicillin Using Triple Therapy with a PPI, Metronidazole and Sitafloxacin

抄録

Eradication of H. pylori in patients allergic to penicillin should be performed using regimens without penicillin derivatives. We treated a total of 28 patients allergic to penicillin with a proton pump inhibitor (PPI), metronidazole (250 mg bid) and sitafloxacin (100 mg bid) for one to two weeks. At four to eight weeks after the treatment, the patients underwent the [¹³C]-urea breath test. The overall eradication rate was 100.0%. Mild adverse events were observed. Triple therapy with a PPI, metronidazole and sitafloxacin is well tolerated and effective for the eradication of H. pylori in patients allergic to penicillin.<br>

収録刊行物

• Internal Medicine

  Internal Medicine 53 (6), 571-575, 2014

  一般社団法人 日本内科学会

キーワード

• penicillin allergy
• <i>H. pylori</i>
• metronidazole
• sitafloxacin

詳細情報

• CRID: 1390001204870258176
• NII論文ID: 130003392718
• DOI: 10.2169/internalmedicine.53.1677
• COI: 1:STN:280:DC%2BC2crjslWnug%3D%3D
• ISSN: 13497235
• ISSN: 09182918
• PubMed: 24633026
• Web Site: https://www.jstage.jst.go.jp/article/internalmedicine/53/6/53_53.1677/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2015048884
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可