A Case Series of Possibly Recrudescent Orientia tsutsugamushi Infection Presenting as Pneumonia

DOI Web Site PubMed 参考文献23件
  • Im Jae-Hyoung
    Department of Internal Medicine, Inha University School of Medicine
  • Baek Ji Hyeon
    Department of Internal Medicine, Inha University School of Medicine
  • Lee Jin-Soo
    Department of Internal Medicine, Inha University School of Medicine
  • Chung Moon-Hyun
    Department of Internal Medicine, Inha University School of Medicine
  • Lee Sun Myoung
    Translation Research Center, Inha University School of Medicine
  • Kang Jae-Seung
    Department of Microbiology, Inha University School of Medicine

書誌事項

タイトル別名
  • A Case Series of Possibly Recrudescent <i>Orientia tsutsugamushi</i> Infection Presenting as Pneumonia

この論文をさがす

抄録

Orientia tsutsugamushi remains latent in humans after scrub typhus. Pneumonia occurs as a complication of scrub typhus in the late-phase disease. However, pneumonia may also occur as a presenting manifestation of O. tsutsugamushi infection. We reviewed the cases of 3 patients with atypical pneumonia who presented at our hospital and were later confirmed to have O. tsutsugamushi infection by serology, nested polymerase chain reaction (PCR), and cell culture. All patients were young adults with no history of scrub typhus, and none claimed to have recently been exposed to areas where scrub typhus is endemic. Two cases occurred in non-outbreak seasons. Furthermore, eschar was not observed. Pneumonia was documented within 4 days after fever onset. The immunoglobulin (Ig) G antibody titers against O. tsutsugamushi were higher than the IgM titers, although the serologic test results were less helpful in the diagnosis. Nested PCR and cell culture of blood specimens confirmed the diagnosis of O. tsutsugamushi infection. These findings suggest that pneumonia can occur as a result of recrudescence of latent O. tsutsugamushi infection.

収録刊行物

参考文献 (23)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ