INOSINE FERMENTATION-PRODUCTION OF INOSINE BY MUTANTS OF BACILLUS SUBTILIS

• AOKI RYOHEI

  Central Research Laboratories of Ajinomoto Co., Inc.

• KONDO YASUHIRO

  Central Research Laboratories of Ajinomoto Co., Inc.

• HIROSE YOSHIO

  Central Research Laboratories of Ajinomoto Co., Inc.

• OKADA HIROSHI

  Central Research Laboratories of Ajinomoto Co., Inc.

書誌事項

タイトル別名

• INOSINE FERMENTATION-PRODUCTION OF INOSINE BY MUTANTS OF <i>BACILLUS SUBTILIS</i>
• IV. SCALE-UP OF INOSINE FERMENTATION

抄録

Using r_ab values, rates of oxygen transfer into sulfite solution, as an index for establishing aeration-agitation, the fermentative production of inosine was scaled up from a flask culture to a 50-k1 tank culture. By applying the optimum condition for the production of inosine obtained with small scale fermentors, the yield of inosine obtained with a 50-k1 fermentor was approximately the same as that from small-scale fermentors. With due consideration to cotton plugs as a barrier of oxygen transfer, the advantage of using r_ab values for aeration-agitation index and for scale-up of aerobic fermentation was discussed.

収録刊行物

• The Journal of General and Applied Microbiology

  The Journal of General and Applied Microbiology 14 (4), 411-416, 1968

  公益財団法人　応用微生物学・分子細胞生物学研究奨励会

キーワード

• Applied Microbiology and Biotechnology
• Microbiology

詳細情報

• CRID: 1390001204147751680
• NII論文ID: 130003399548
• DOI: 10.2323/jgam.14.411
• COI: 1:CAS:528:DyaF1MXns1ChtA%3D%3D
• ISSN: 13498037
• ISSN: 00221260
• Web Site: http://www.jstage.jst.go.jp/article/jgam1955/14/4/14_4_411/_pdf
• 本文言語コード: en
• データソース種別:
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  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可