乳腺ｍｕｃｏｃｅｌｅ‐ｌｉｋｅ　ｔｕｍｏｒの１例　　免疫組織化学的検討を中心に

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タイトル別名
  • A case of mucocele-like tumor of the breast an immunohistochemical analysis.
  • AN IMMUNOHISTOCHEMICAL ANALYSIS
  • 免疫組織化学的検討を中心に

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A case of mucocele-like tumor of the breast is presented. A 47-year-old woman sas seferred to the hospital because of a right breast mass which was pointed out at a mass acreening test for breast cancer. A possibility of breast cancer could not be ruled out by mammography and ultrasoundgraphy of the breast. Aspiration biopsy and cytological examination revealed mucin and epithelial cels which did not show malignant feature. Lumpectomy was performed. Pathological examination using the formalin-fixed and parafin-embeded specimen showed mucocele-like tumor (MLT) of the breast. MLT of the breast is considered binign lesion. However, recently MLTs with mucinous carcinoma or ductal carcinoma in situ have been reported and some researchers have advocated that it is on the borderline between benign and malignant lesions. The case also showed a small part of papillary lesion in the cyst wall. Then, an immunohistological analysis was made. Estrogen receptor was weakly positive, and mutant p53, Ki-67, and c-erbB-2 were negative. These data suggested that the degree of malignancy of the MLT was very low. However, the biological behavior of MLT in the breast is still unknown. Further studies to verify the malignancy of MLT are required for the proper treatment and follow up of this disease.

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