A CASE OF SOMATOSTATIN PRODUCING ASYMPTOMATIC PANCREATIC ENDOCRINE TUMOR

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  • ソマトスタチン産生非症候性すい内分泌腫ようの１例

Abstract

We report a case of asymptomatic pancreatic endocrine tumor with some bibliographical comments. A 65-year-old woman was seen at the our institute because she was pointed out occult bloody stool on a regular medical check up. Plain abdominal CT revealed a low density mass of the pancreatic head and the tumor was enhanced. On abdominal magnetic resonance imaging scan, T1-weighted image revealed a low density mass, and T2-weighted image revealed the high density mass. On ERP examination, the main pancreatic duct was compressed by the tumor. Angiography showed a hypervascular tumor. We suspected that the tumor was pancreatic endocrine tumor, and serum hormone levels were measured. Only a slight increase of serum somatostatin level was noted. She was preoperatively diagnosed as having asymptomatic pancreatic endocrine tumor and a pylorus preserving pancreatoduodenectomy was performed. The well-defined solid tumor with the diameter of 27mm was situated at the pancreatic head. In immunohistochemical stainings, the tumor cells were positive for chromogranin and somotostatin.

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