書誌事項
- タイトル別名
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- Three Autopsied Cases of Generalized Mucormycosis with Lung Involvement Complicating Lymphoma and Leukemia
抄録
Pulmonary involvement with mucormycosis is quite uncommon, but the incidence has been increasingly recognized, especially in patients with leukemia or lymphoma. We report three autopsied cases of generalized mucormycosis (phycomycosis) in patients with non-Hodgkin's lymphoma, acute exacerbation of chronic myelogenous leukemia, and acute myelogenous leukemia. All patients had abnormal lung shadows and high fever unresponsive to broad-spectrum antibiotics and trimethoprim-sulfamethoxazole.<br>Their chest X-ray findings were as follows;<br>Cases 1: Diffuse ground glass appearance with nodular density at the right hulim suggesting hemorrhagic infarction.<br>Cases 2: Diffuse ground glass appearance.<br>Cases 3: Several patchy infiltrates in the right lung and a large nodular density with cavities in the left lung field.<br>In two of three cases, flucytosine was administered without any remarkable effect. Histological examination revealed multiple infarction and thrombosis in various parts of pulmonary arteries in which broad and nonseptate hyphae were found. Sputum cultures were performed in all cases white they were alive, but no pathognomonic organism was found. Premortal diagnosis of mucormycosis is extremely difficult, but one possible way of diagnosis might be by lung perfusion scanning using 131I-MAA.
収録刊行物
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- 日本胸部疾患学会雑誌
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日本胸部疾患学会雑誌 22 (3), 214-219, 1984
社団法人 日本呼吸器学会