An acetylcholine-induced potassium current in tail sensory neurons in the pleural ganglion of Aplysia.

• ICHINOSE Mitsuyuki

  Department of Physiology, Shimane Medical University

• SAWADA Masashi

  Department of Physiology, Shimane Medical University

• MAENO Takashi

  Department of Physiology, Shimane Medical University

抄録

Acetylcholine (ACh) induces a hyperpolarization during current clamp and an outward current during voltage clamp in tail sensory neurons of Aplysia kurodai. This response was proved to be produced by a specific increase in membrane permeability toward potassium ions. the cholinergic antagonists, d-tubocurarine chloride (d-TC), and atropine mildly reduced the ACh response, while tetraethylammonium (TEA) most effectively blocked this response. These findings provide evidence that tail sensory neurons have the inhibitory ACh receptor in addition to the known receptors for serotonin (5-HT), small cardioactive peptide_B (SCP_B), and neuropeptide Phe-Met-Arg-Phe-NH₂ (FMRFamide).

収録刊行物

• The Japanese Journal of Physiology

  The Japanese Journal of Physiology 38 (4), 563-568, 1988

  一般社団法人　日本生理学会

キーワード

• <i>Aplysia</i>
• sensory neuron
• acetylcholine

詳細情報

• CRID: 1390001205043827200
• NII論文ID: 130003477337
• DOI: 10.2170/jjphysiol.38.563
• COI: 1:STN:280:BiaC2sbjvVM%3D
• ISSN: 18811396
• ISSN: 0021521X
• PubMed: 3236575
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可