大型ピロプラズマ (Babesia ovata) 実験感染牛に対する摘脾およびデキサメサゾン投与の影響

DOI Web Site Web Site PubMed 被引用文献2件

書誌事項

タイトル別名
  • Effect of Splenectomy and Dexamethasone Administration on Cattle Experimentally Infected with Babesia ovata
  • オオガタ ピロプラズマ Babesia ovata ジッケン カンセン ウシ

この論文をさがす

抄録

Clinical, hematological, and immunoserological studies were made on the effect of splenectomy and dexamethasone (DM) administration on 26 cattle experimentally infected with Babesia ovata. Four intact cattle serving as controls recovered from temporary parasitemia and mild anemia with immunofluorescent antibody (IFA) titers rapidly rising. Nine cattle infected after splenectomy showed severe anemia because of a marked increase in severity of parasitemia. Five of them died or were killed in the moribund stage. No antibody response was observed in two of the five cattle. Eight splenectomised cattle were injected intramuscularly one to four times with DM (0.lmg/kg/day) after inoculation. Parasitemia always reached markedly high levels followed by fatality. Four cattle of them presented no IFA response. Two carrier cattle were treated with DM (0.1mg/kg/day) for 7 days. They manifested no parasitemia and their IFA titers were not changed. On the other hand, the relapse of parasitemia occurred in three cattle splenectomized in the carrier stage. Two of these cattle were treated consecutively with DM (0.1 and 0.15mg/kg/day) for 7 and 9 days, respectively. They showed no noticeable increase in severity of parasitemia, as compared with the control which had not been treated with DM. Discussion was made on the roles of humoral and celluIar factors and the importance of the spleen for protection of cattle from Babesia ovata infection.

収録刊行物

被引用文献 (2)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ