地方病性ウシ白血病における補体依存抗体細胞障害試験および免疫蛍光法によって検出された腫瘍関連抗原
書誌事項
- タイトル別名
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- Tumor-associated antigen detected by complement-dependent antibody cytotoxicity test and immunofluorescence test in enzootic bovine lymphosarcoma.
- 地方病性ウシ白血病における補体依存抗体細胞障害試験および免疫蛍光法によって検出された腫瘍関連抗原〔英文〕
- チホウビョウセイ ウシ ハッケツビョウ ニ オケル ホタイ イゾン コウタイ
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抄録
Tumor-associated antigens were studied on the neoplastic cells of cattle affected with bovine lymphosarcoma (BL) by complement-dependent antibody cytotoxicity (CDAC) test and immunofluorescence (IF) test using antiserum produced in rabbits which were immunized with tumors from four cows. The antiserum from rabbits was absorbed with erythrocytes and pooled cells of lymph nodes from normal cows. Neoplastic cells from 18 of 21 cases affected with enzootic BL (EBL) showed cytotoxic reaction by CDAC test, but those were negative from one case of calf type BL (CBL). Cytoplasmic antigen was detected by IF test in acetone-fixed neoplastic cells from all 52 EBL cows examined. No reaction was observed in lymphocytes of normal 9 cows and 3 fetuses from EBL cows as well as in neoplastic cells of 3 CBL calves. Fluorescence was observed in 37% to 97% of peripheral blood lymphocytes (PBL) from all EBL cases examined. None of PBL from 7 normal cows showed positive reaction.
収録刊行物
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- 日本獸醫學雜誌(The Japanese Journal of Veterinary Science)
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日本獸醫學雜誌(The Japanese Journal of Veterinary Science) 45 (2), 195-202, 1983
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206421628032
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- NII論文ID
- 110003947809
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- NII書誌ID
- AN00191788
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- COI
- 1:STN:280:DyaL2c%2Fjslaiuw%3D%3D
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- ISSN
- 18811442
- 00215295
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- NDL書誌ID
- 2590052
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- PubMed
- 6355592
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可