ブタの腎クリアランス値測定のための慢性尿管カテーテル装着法
書誌事項
- タイトル別名
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- Use of a chronic ureter cannula in the pig for the determination of renal clearance.
- ブタの腎クリアランス値測定のための慢性尿管カテーテル装着法〔英文〕
- ブタ ノ ジン クリアランスチ ソクテイ ノ タメ ノ マンセイ ニョウカン
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The surgical implantation of chronic ureter cannula to determine the renal clearance was evaluated using 24 pigs. The silicon tubing was surgically implanted into both ureters of each pigs. Two types of thick tubing (the inside diameter 1.0 or 2.5mm and the outside diameter 4.0mm) were used for these cannulas. The tubing was exposed out of the pig's body on the flank, on the hypogastric zone near the umbilicus, or near the groin. The following steps were effective to minimize the opportunity of a bacterial infection in the kidney and to maintain the functional integrity of the chronic ureter cannula for as longer period as possible: 1) to use the tubing of larger opening as the ureter cannula, 2) to expose the tubing from the hypogastric zone near the groin, and 3) to apply the disinfectant frequently to the incision sites, cannula outlets and pig's metabolic cage. The oral ingestion of the GGES solution increased the urinary volume, which might in turn have resulted in the effective rinsing of the kidney and the chronic ureter cannula. The cannula served satisfactorily for more than 3 weeks in 13 of the pigs, up to a maximum of 7 weeks. The PSP clearances values were low during the first week of the postoperative period, which may be attributed to surgical stress. The chronic ureter cannula, associated with the postoperative period of more than 1 week, can be recommended for the evaluation of the renal clearance of drugs in the pig.
収録刊行物
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- 日本獸醫學雜誌(The Japanese Journal of Veterinary Science)
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日本獸醫學雜誌(The Japanese Journal of Veterinary Science) 52 (3), 479-485, 1990
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206422357376
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- NII論文ID
- 110003918220
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- NII書誌ID
- AN00191788
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- COI
- 1:STN:280:DyaK3czkvVSntA%3D%3D
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- ISSN
- 18811442
- 00215295
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- NDL書誌ID
- 3671110
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- PubMed
- 2385031
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
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- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可