<I>In Vivo</I> Formation of Transmissible Resistance Factor by Recombination between Nontransmissible Resistance Factor and Col B Factor

• KAMEDA Mitsuo

  Department of Microbiology, School of Medicine Gunma University

• SUZUKI Kaname

  Department of Microbiology, School of Medicine Gunma University

• MITSUHASHI Susumu

  Department of Microbiology, School of Medicine Gunma University

抄録

Germ-free swine were artificially contaminated with tetracycline (TC) sensitive strains of Escherichia coli and Klebsiella pneumoniae. One of these strains, E. coli 3306, was infected with a plasmid carrying kanamycin (KM) resistance, i.e., T-kan factor. Another strain, E. coli P-5, carried a conjugally transferable Col B factor. Among the nine strains used, onlyE. coli P-38 became TC-resistant after TC administration. Three types of TC-resistant E. coli P-38 strains were found; (a) one strain carried nontransferable TC resistance and could not produce colicin, (b) one strain carried TC resistance with a high transmission frequency which could not produce colicin, and (c) one strain carried TC resistance with a low transmission frequency that could produce colicin B. Genetic studies disclosed that the transmissible TC resistance factors, i.e., Rn_ms105 (group b) and R_ms104 (group c), were formed by recombination between Col B factor and nontransmissible TC-resistance (tet) determinant which appeared in E. coli P-38 mutants.

収録刊行物

• MICROBIOLOGY and IMMUNOLOGY

  MICROBIOLOGY and IMMUNOLOGY 22 (4), 173-180, 1978

  Center For Academic Publications Japan

詳細情報

• CRID: 1571698603035133696
• NII論文ID: 130003482702
• ISSN: 03855600
• Web Site: https://jlc.jst.go.jp/DN/JALC/00308473360?from=CiNii
• 本文言語コード: en
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