The Structure of Marek's Disease Virus DNA
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- HAYASHI Masanobu
- Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Hokkaido University
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- JESSIP John
- Department of Virology, Showa University Research Institute for Biomedicine in Florida
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- FUKUCHI Kunihiko
- Department of Virology, Showa University Research Institute for Biomedicine in Florida
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- SMITH Mary
- Department of Virology, Showa University Research Institute for Biomedicine in Florida
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- TANAKA Akiko
- Department of Virology, Showa University Research Institute for Biomedicine in Florida
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- NONOYAMA Meihan
- Department of Virology, Showa University Research Institute for Biomedicine in Florida
抄録
The structure of Marek's disease virus (MDV) DNA was investigated by using Southern blot hybridization analysis. A heterogeneous region was observed in the inverted repeats region, IRS and TRS, as well as in the TRL and IRL. The results of DNA sequencing of the heterogeneous region showed that the heterogeneity of IRS and TRS was due to amplification of a 178-bp repeat sequence. Amplification of IRS and TRS was found in viral DNA from both pathogenic and nonpathogenic strains. The structure of DNA from the latent MDV genome present in established lymphoblastic cells was also determined. Amplification of the 132-bp repeat sequence in IRL and TRL was not found in latent MDV DNA of established lymphoblastic cells, whereas amplification of the 178-bp repeat sequence in IRS and TRS was found in the same DNA.
収録刊行物
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- MICROBIOLOGY and IMMUNOLOGY
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MICROBIOLOGY and IMMUNOLOGY 32 (3), 265-274, 1988
Center For Academic Publications Japan
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詳細情報 詳細情報について
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- CRID
- 1570291228151705856
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- NII論文ID
- 130003483435
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- ISSN
- 03855600
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- 本文言語コード
- en
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- データソース種別
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- CiNii Articles