Toxicity of <i>Microcystis aeruginosa</i> K-139 Strain

• NAKANO Masayasu

  Department of Microbiology, Jichi Medical School

• NAKANO Yasunobu

  Department of Microbiology, Jichi Medical School

• SAITO-TAKI Tatsuo

  Department of Microbiology, Jichi Medical School

• MORI Naoyoshi

  Institute of Basic Medical Sciences, University of Tsukuba

• KOJIMA Mizu

  Mito Saiseikai General Hospital

• OHTAKE Akio

  Department of Agricultural Chemistry, Ibaraki University

• SHIRAI Makoto

  Department of Agricultural Chemistry, Ibaraki University

抄録

Toxicity of the cells of a newly established axenic Microcystis aeruginosa K-139 strain to mice was studied. LD₅₀ of the cells harvested in the mid-log phase was 7.3mg/kg. The organs of acute dead mice were examined histopathologically. The blood congestion and necrosis of the parenchymal cells around the central veins in the liver were observed, but other organs seemed to be normal. The liver damage was confirmed by the tests of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) activities in the sera of the mice after the injection with the K-139 cells. Furthermore, the K-139 cells were capable of inducing interleukin 1 (IL-1) production by peritoneal macrophages in vitro.

収録刊行物

• MICROBIOLOGY and IMMUNOLOGY

  MICROBIOLOGY and IMMUNOLOGY 33 (9), 787-792, 1989

  Center For Academic Publications Japan

詳細情報

• CRID: 1570009753174975616
• NII論文ID: 130003483611
• ISSN: 03855600
• Web Site: https://jlc.jst.go.jp/DN/JALC/00173973606?from=CiNii
• 本文言語コード: en
• データソース種別:
  • CiNii Articles