Acceleration of Adenovirus Replication and Increased Virion Production by Treatment with the Steroid Hormone 17 Beta-Estradiol

• JAMES Calvin B. L.

  Department of Zoology and Biomedical Sciences, Ohio University

• VANDERPOOL Eustace A.

  Department of Microbiology, College of Medicine, Howard University

• ROANE Philip

  Department of Microbiology, College of Medicine, Howard University

抄録

We report here that concentration of an estrogen known to promote enhanced transformation and to increase oncogenicity of rat embryo cells, accelerate the production and increase the yield of progeny virions in adenovirus type 12 (Ad 12)-infected HEp-2 cells. Further, measurement of the incorporation of radioactive RNA and DNA precursors indicated that macromolecular synthesis in the estrogen-treated, infected cells was accelerated. Possible explanations for this observation are discussed.

収録刊行物

• MICROBIOLOGY and IMMUNOLOGY

  MICROBIOLOGY and IMMUNOLOGY 36 (1), 99-103, 1992

  Center For Academic Publications Japan

詳細情報

• CRID: 1572543027964477952
• NII論文ID: 130003483821
• ISSN: 03855600
• Web Site: https://jlc.jst.go.jp/DN/JALC/00078544635?from=CiNii
• 本文言語コード: en
• データソース種別:
  • CiNii Articles