An ATP Bioluminescence Assay Applicable to Rapid Fluconazole Susceptibility Testing of Dermatophytes
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- Yoshida Tatsumi
- Research Center for Medical Mycology, Teikyo University
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- Uchida Katsuhisa
- Research Center for Medical Mycology, Teikyo University
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- Yamaguchi Hideyo
- Research Center for Medical Mycology, Teikyo University
抄録
An ATP bioluminescence assay as a rapid reference method for fluconazole (FLCZ) susceptibility testing of dermatophytes, as well as yeasts, was developed and evaluated by comparing it with viability, turbidity and fungal protein content-based conventional methods. FLCZ susceptibility results obtained with strains of Candida albicans and dermatophytes by the bioluminescence method in high-resolution medium were well correlated with those obtained by conventional methods currently used in clinical microbiology laboratories or reported previously, including a broth dilution method by the National Committee for Clinical Laboratory Standards (NCCLS). Thus, ATP bioluminescence assay can be used to monitor fungal growth in liquid culture media. The procedure has considerable potential for the rapid testing of FLCZ susceptibility of dermatophytes and other fungi.
収録刊行物
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- MICROBIOLOGY and IMMUNOLOGY
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MICROBIOLOGY and IMMUNOLOGY 41 (5), 377-386, 1997
Center For Academic Publications Japan
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詳細情報 詳細情報について
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- CRID
- 1570854178104751360
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- NII論文ID
- 130003484514
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- ISSN
- 03855600
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- 本文言語コード
- en
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- データソース種別
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- CiNii Articles