Enhancement of pentose phosphate pathway in vascular intima from diabetic rabbit.

• SATO TOKUTARO

  The Second Department of Internal Medicine, Tohoku University School of Medicine

• SASAKI HISAO

  the Second Department of Surgery, Tohoku University School of Medicine

• WATANABE RYOICHIRO

  The Second Department of Internal Medicine, Tohoku University School of Medicine

• YOSHINAGA KAORU

  The Second Department of Internal Medicine, Tohoku University School of Medicine

抄録

SATO, T., SASAKI, H., WATANABE, R. and YOSHINAGA, K. Enhancement of Pentose Phosphate Pathway in Vascular Intima from Diabetic Rabbit. Tohoku J. exp. Med., 1988, 155 (1), 97-100-Activity of pentose phosphate pathway in the intima grown inside vascular prosthesis was studied in alloxan diabetic rabbits. Ratio of ¹⁴CO₂ production from 1-¹⁴C-glucose and 6-¹⁴C-glucose was 7.8 in the nondiabetic group and 78.9 in the diabetic group. Statistically positive correlation was found between the ratio and the levels of blood glucose or plasma triglyceride. These results suggest that pentose phosphate pathway in the vascular intima is active, and enhanced to a great extent in diabetes.

収録刊行物

• The Tohoku Journal of Experimental Medicine

  The Tohoku Journal of Experimental Medicine 155 (1), 97-100, 1988

  東北ジャーナル刊行会

キーワード

• pentose phosphate pathway
• diabetes
• intima

詳細情報

• CRID: 1390001204240077952
• NII論文ID: 130003493972
• DOI: 10.1620/tjem.155.97
• COI: 1:CAS:528:DyaL1cXltVynsbc%3D
• ISSN: 13493329
• ISSN: 00408727
• PubMed: 3137697
• Web Site: http://www.jstage.jst.go.jp/article/tjem1920/155/1/155_1_97/_pdf
• 本文言語コード: en
• データソース種別:
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  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可