Pepticinnamins, new farnesyl-protein transferase inhibitors produced by an actinomycete. II. Structural elucidation of pepticinnamin E.
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- SHIOMI KAZURO
- Research Center for Biological Function, The Kitasato Institute
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- YANG HONG
- Research Center for Biological Function, The Kitasato Institute
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- INOKOSHI JUNJI
- Research Center for Biological Function, The Kitasato Institute
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- PYL DIDIER VAN DER
- Research Center for Biological Function, The Kitasato Institute
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- NAKAGAWA AKIRA
- School of Science and Engineering, Teikyo University
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- TAKESHIMA HIDEO
- Research Center for Biological Function, The Kitasato Institute
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- OMURA SATOSHI
- Research Center for Biological Function, The Kitasato Institute
書誌事項
- タイトル別名
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- II. STRUCTURAL ELUCIDATION OF PEPTJCINNAMIN E
抄録
Structure of novel farnesyl transferase inhibitor, pepticinnamin E, is elucidated by NMR study. Pepticinnamin E is composed of five amino acids and o-pentenylcinnamic acid, having a molecular weight of 907. C-terminal glycylserine of the compounds is in the cyclized diketopiperazine form.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 46 (2), 229-234, 1993
公益財団法人 日本感染症医薬品協会