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- MATSUBARA Shiro
- Department of Neurology, Toranomon Hospital
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- TABUCHI Yasunori
- Department of Neurology, Toranomon Hospital
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- NOZAWA Taneyoshi
- Department of Neurology, Toranomon Hospital
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- TANABE Hitoshi
- Department of Neurology, Toranomon Hospital
書誌事項
- タイトル別名
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- Muscle Atrophy in a Case of Acute Disse
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A case of acute disseminated encephalomyelitis (ADEM) accompanied by muscle atrophy is reported. A man of 30 was admitted with acute onset of clouded consciousness, fever, paraplegia and sensory loss, following an upper respiratory tract infection. A week later, marked muscle atrophy was noticed in both legs. A biopsy of the quadriceps femoris muscle showed groups of small angular fibres indicating neuropathic change, and also fibres with round contour and varying diameter suggestive of myopathic change. Some fibres contained vacuoles, basophilic material and or eosinophilic mass. Histochemical examinations suggested that the basophilic material contained mitochondria, lipid and glycogen, while the eosinophilic mass was regarded as hyaline degeneration. Cellular infitration was not observed in the interstitium. Electron micrographs showed disarray and loss of myofibrils, abundant mitochondria and glycogen granules, myelin figures and honeycomb structures. The cause of the muscle changes is uncertain. However, as conceivable causal mechanisms, the possibility of polymyositis is discussed as well as the effect of immobilization and probable involvement of the nerve roots and peripheral nerves.
収録刊行物
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- Japanese Journal of Medicine
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Japanese Journal of Medicine 19 (3), 212-219, 1980
社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390001204867811712
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- NII論文ID
- 130003513625
- 40005320470
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- NII書誌ID
- AA00691133
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- ISSN
- 1881123X
- 00215120
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- NDL書誌ID
- 2219318
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
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- 抄録ライセンスフラグ
- 使用不可