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- AOKI Noriaki
- Department of Emergency and Critical Care Medicine, Kitasato University School of Medicine
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- SOMA Kazui
- Department of Emergency and Critical Care Medicine, Kitasato University School of Medicine
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- KATAGIRI Hiroshi
- Department of Public Health, Kitasato University School of Medicine
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- AIZAWA Yoshiharu
- Department of Preventive Medicine and Public Health, Kitasato University School of Medicine
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- KADOWAKI Takehiro
- Department of Preventive Medicine and Public Health, Kitasato University School of Medicine
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- OHWADA Takashi
- Department of Emergency and Critical Care Medicine, Kitasato University School of Medicine
書誌事項
- タイトル別名
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- Pulmonary Hemodynamic Effects of 1 1 1
この論文をさがす
抄録
We examined the hemodynamic effects of 1, 1, 1-trichioroethane (TCE) inhalation in anesthetized dogs in acute inhalation experiments. Six adult mongrel dogs with spontaneous respiration were intubated, connected to a one-way valve. TCE was delivered by the tubular system connected to a 30-liter tedlar bag reservoir filled with 1v/v% of TCE. After TCE inhalation, the animals revealed a significant decrease in systemic arterial pressure following a decrease in systemic vascular resistance. Pulmonary arterial pressure, pulmonary vascular resistance and right cardiac work increased significantly. These changes were compatible with clinical manifestations of TCE intoxication in human beings. In conclusion, inhalation of TCE may not only decrease peripheral vascular resistance, but also induce transient disturbance of pulmonary blood flow with subsequent pressure overloading in the right ventricle.
収録刊行物
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- Industrial health
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Industrial health 35 (4), 451-455, 1997
独立行政法人 労働者健康安全機構 労働安全衛生総合研究所
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282679256724864
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- NII論文ID
- 130003550813
- 110000016722
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- NII書誌ID
- AA00672955
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- ISSN
- 18808026
- 00198366
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- NDL書誌ID
- 4405856
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- PubMed
- 9348715
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可