Some Chromosomal Studies on Patients with Infectious Hepatitis

AYA Takao, MAKINO Sajiro, HIRAYAMA Akio

doi:10.2183/pjab1945.42.1088

Some Chromosomal Studies on Patients with Infectious Hepatitis

DOI Web Site 被引用文献1件参考文献7件

AYA Takao

Zoological Institute, Hokkaido University
MAKINO Sajiro

Zoological Institute, Hokkaido University
HIRAYAMA Akio

Tonan Hospital

抄録

Thirteen patients with infectious hepatitis, and 7 controls were scanned for chromosome abnormality in cultured leucocytes. Chromatid breaks occurred most frequently in both patients and controls, with less frequent isochromatid breaks and acentric fragments. Interchanges and dicentrics seldom occurred. The frequency of chromosome breaks was significantly higher in patients' cultures than in controls. A relatively significant excess of breaks occurred in the middle segments of the long arms of chromosomes 4-5.