右副腎転移を伴い急速に進展した小腸malignant gastrointestinal stromal tumorの1例

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  • A CASE OF HIGHLY MALIGNANT GASTROINTESTINAL STROMAL TUMOR WITH METASTASIS OF THE RIGHT ADRENAL GLAND

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A 62-year-old man admitted to the hospital because of right shoulder pain was found to have a right adrenal tumor 6 cm in diameter on computed tomography (CT) and magnetic resonance imaging (MRI) scan. He was sent to other hospital for an endocrinological examination which revealed no abnormal findings, so a laparoscopic biopsy was conducted. Histopathological diagnosis was a metastatic tumor and he was sent to the hospital again. A movable tumor was palpable in the lower abdomen and an abdominal CT scan showed a tumor 10 cm in diameter similar to the right adrenal tumor. With a diagnosis of a small intestinal tumor and metastasis of the right adnenal gland, we conducted a resection of the small intestinal tumor and a right total adrenalectomy with the right lobe of the liver and right kidney. Macroscopically, the small intestinal tumor showed ulceration on the mucosal side, hematoma, and multiple small abscesses, and the right adrenal tumor was spongiform with hemorrhage. Immunohistochemical findings showed positive c-kit and focally positive SMA. Gastrointestinal stromal tumor was diagnosed. The tumor relapsed in a short time after the surgery and advanced rapidly. We inferred that the patient had a highly malignant gastrointestinal stromal tumor.

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