Ｃｒｏｓｓｅｄ　ｃｅｒｅｂｅｌｌａｒ　ｄｉａｓｃｈｉｓｉｓの臨床的検討

• 羽生 春夫

  東京医科大学老年科

• 山口 克彦

  東京医科大学老年科

• 岩本 俊彦

  東京医科大学老年科

• 勝沼 英宇

  東京医科大学老年科

• 鈴木 孝成

  同 放射線科

書誌事項

タイトル別名

• A clinical study of crossed cerebellar diaschisis.

抄録

The phenomenon of decreased blood flow and metabolism in contralateral cerebellum following supratentorial lesions has been termed crossed cerebellar diaschisis (CCD) by Baron et al. Many factors including the location and size of the lesion, the presence of motor paralysis, and the time after onset have been considered to be important in the development of CCD. In order to elucidate what factors contribute to the development of CCD, 43 patients suffering from a unilateral supratentorial disorder were studied using a single photon emission computerized tomography with ¹²³I-iodoamphetamine. The phenomenon of CCD was here defined as significant contralateral cerebellar hypoperfusion.<BR>CCD was observed in not only cerebral infarction (58.1% of patients) and cerebral hemorrhage (66.7%), but also brain tumor (50.0%) and chronic subdural hematoma (25.0%). Therefore, the localized and acute brain lesion was not necessarily essential for the development of CCD. Analysis by a quantification theory (Type 2) in 31 patients with cerebral infarction showed that the location and size of the lesion appeared to greatly contribute to CCD rather than the presence of motor paralysis and the time after onset. CCD was present more frequent and prominent in the patients with either extensive multilobar infarction or relatively larger deep infarction. Serial studies showed transient phenomena in smaller deep infarctions, but this phenomena tended to persist for a long time in larger infarctions suggesting transneuronal degeneration of the corticopontocerebellar pathway.<BR>It is likely that the pathophysiological mechanism of this phenomenon consists of reversible diaschisis and irreversible degeneration depending on the location and size of the lesion.

収録刊行物

• 脳卒中

  脳卒中 11 (1), 32-39, 1989

  一般社団法人 日本脳卒中学会

キーワード

• crossed cerebellar diaschisis
• single photon emission computed tomography
• N-isopropyl-p-(<SUP>133</SUP>I) iodoamphetamine
• cerebrovascular disease

詳細情報

• CRID: 1390001204640167168
• NII論文ID: 130003630774
• DOI: 10.3995/jstroke.11.32
• ISSN: 18831923
• ISSN: 09120726
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可