書誌事項
- タイトル別名
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- Favorable response obtained by low dose chemotherapy in an elderly patient with extensive small cell lung cancer and renal dysfunction
- テイヨウリョウ カガク リョウホウ ガ ソウコウ シタ ジンキノウ ショウガイ オ トモナッタ コウレイシャ ショウサイボウ ハイガン ノ 1レイ
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An 82-year-old man with extensive small cell lung cancer was treated with 2 courses of low dose CPT-11 (40mg/body, day 1, 8 and 15) and carboplatin (100mg/body, day 1). The reduction in tumor sizes evaluated by two-direction measurement was 88%. His creatinin clearance rates before and after chemotherapy were 20 and 28ml/min, respectively. Temporary leukopenia (900/μl) during the second course of chemotherapy was quickly reversed by the administration of G-CSF, without any episode of infection. Low dose CPT-11 and carboplatin seems to be a promising regimen for elderly patients with small cell lung cancer and renal dysfunction. Cancer tends to increase in old age groups. We consider that it is necessary to examine ideal low dose chemotherapies that can be effective yet preserve quality of life.
収録刊行物
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- 日本老年医学会雑誌
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日本老年医学会雑誌 42 (4), 453-456, 2005
一般社団法人 日本老年医学会
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詳細情報 詳細情報について
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- CRID
- 1390001205024795392
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- NII論文ID
- 130003653031
- 40006869786
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- NII書誌ID
- AN00199010
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- NDL書誌ID
- 7443266
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- ISSN
- 03009173
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- PubMed
- 16117488
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可